李奎亮 讲师

一、基本信息

李奎亮（1997-），男，河南周口人，博士。2018年6月毕业于苏州大学高分子材料与工程专业，获工学学士学位。2018年9月至2023年6月在中国科学技术大学攻读有机化学博士研究生，获理学博士学位。

二、研究方向

有机合成方法学，计算有机化学

三、主要成果

（一）研究项目

中国科学技术大学先进技术研究院科研项目（TD00322001H），防爆电池箱的技术开发，结题，主持。

（二）论文论著

1. Kuiliang Li, Siyu Gao, Zhenggen Zha, Zhiyong Wang*. Construction of chiral N,O-hemiaminals via a copper-catalyzed enantioselective Michael/N-hemiacetalization cascade reaction.         Org. Biomol. Chem. 2023, 21, 4404-4408.

2. Kuiliang Li, Xiang Sun, Shuangshuang Zhao, Tong Li, Zhenggen Zha, Zhiyong Wang*. Zn-Catalyzed enantioselective allylation and allenylation of isatins by virtue of a proline-derived chiral ligand.        Chem. Commun. 2022, 58, 2156-2159.

3. Kuiliang Li, Xiang Sun, Linge Li, Zhenggen Zha, Feng-Lian Zhang, Zhiyong Wang. Stereoselective Copper-Catalyzed Direct Aldol Reaction of β,γ-Unsaturated α-Ketoesters with Coumaran-3-Ones. Chem. Eur. J. 2021, 27, 581-584.

4. Shuangshuang Zhao^†, Kuiliang Li^†, Xiang Sun, Zhenggen Zha, Zhiyong Wang*. Copper-Catalyzed Stereoselective [4+2] Cycloaddition of beta,gamma-Unsaturated α-Keto Esters and 2-Vinylpyrroles in Water. Org. Lett. 2022, 24, 4224-4228.

5. Weizhi Gu, Jindong Li, Kuiliang Li, Qi Sun, Tong Li, Zhenggen Zha, Zhiyong Wang*. Construction of a Chiral ß-Fluoroamine by Asymmetric Mannich Reaction of 2-Fluoroindanone with Pyrazolinone Ketimines. J. Org. Chem. 2023, 88, 7736-7747.

6. Xiang Sun, Kuiliang Li, Shuangshuang Zhao, Zhenggen Zha, Zhiyong Wang*. Construction of chiral 3-alkenyl-3-substituted oxindoles by stereoselective direct alkenylation of isatin derivatives and 3-vinylindoles. Chinese Chem. Lett. 2022, 33, 5106-5110.

7. Ning Li, Wenjing Lu, Weizhi Gu, Kuiliang Li, Jindong Li, Yangmian Lu, Zhenggen Zha, Zhiyong Wang*. Construction of Spirocyclic Oxindole Derivatives by Copper-Catalyzed Enantioselective Michael/Hemiketalization in Aqueous Media. Chem. Commun. 2022, 58, 10957-10960.

8. John Kamanda Mansaray, Yekai Huang, Kuiliang Li, Xiang Sun, Zhenggen Zha, Zhiyong Wang*. Efficient enantioselective synthesis of trisubstituted gamma-lactam via the Michael addition reaction of 2,3-dioxopyrrolidine with indole in aqueous media. Org. Biomol. Chem. 2022, 20, 5510-5514.

9. Yu Yang, Liyan Liu, Kuiliang Li, Zhenggen Zha, Qi Sun*, Zhiyong Wang*. Iodine-mediated oxythiolation of o-vinylanilides with disulfides for the synthesis of benzoxazines. RSC Advances 2022, 12, 7347-7351.

10. Zhibin Li, Yan Zhang, Kuiliang Li, Zhenghong Zhou, Zhenggen Zha*, Zhiyong Wang*. Selective electrochemical oxidation of aromatic hydrocarbons and preparation of mono/multi-carbonyl compounds.        Sci. China Chem. 2021, 64, 2134-2141.

11. Xinping Liang, Yang Gui, Kuiliang Li, Jindong Li, Zhenggen Zha, Lei Shi*, Zhiyong Wang*. A novel chiral surfactant-type metallomicellar catalyst for asymmetric Michael addition in water. Chem. Commun. 2020, 56, 11118-11121.

12. Yang Gui, Xinping Liang, Yanan Li, Kuiliang Li, Zhenggen Zha, Zhiyong Wang. Asymmetric synthesis of fluoroalkylated N,O-ketals via an organocatalytic dehydration/aminalization/aza-Michael desymmetrization. Org. Chem. Front 2019, 6, 942-945.

（三）授权专利

1. 一种合成含手性叔醇结构的3-香豆冉酮类化合物的方法，CN112898253A.

2. 一种合成3-羟基-3-烯丙基氧化吲哚和3-羟基-3-联烯基氧化吲哚的方法，CN114437117A.

3. 一种阻燃剂、制法、含上述阻燃剂的涂层及含阻燃涂层的防爆电池箱, CN114958139A.

四、联系方式

电子邮箱：likuil@mail.ustc.edu.cn；likuil@aust.edu.cn